Senescent accelerated prone 8 (SAMP8) mice as a model of age dependent neuroinflammation

Senescent accelerated prone 8 (SAMP8) mice as a model of age dependent neuroinflammation

Abstract Background Aging and age-related diseases are strong risk factors for the development of neurodegenerative diseases. Neuroinflammation (NIF), as the brain’s immune response, plays an important role in aged associated degeneration of central nervous system (CNS). There is a need for well cha...

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Bibliographic Details
Main Authors: Andrés Fernández, Elena Quintana, Patricia Velasco, Belén Moreno-Jimenez, Belén de Andrés, Maria Luisa Gaspar, Isabel Liste, Marçal Vilar, Helena Mira, Eva Cano
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Neuroinflammation
Subjects:
Aging
Brain myeloid cells
Microglia
Inflammation
IL-1β
SAMP8
Online Access:https://doi.org/10.1186/s12974-021-02104-3

Internet

https://doi.org/10.1186/s12974-021-02104-3

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