Differential Downregulation of E-Cadherin and Desmoglein by Epidermal Growth Factor

Modulation of cell : cell junctions is a key event in cutaneous wound repair. In this study we report that activation of the epidermal growth factor (EGF) receptor disrupts cel : cell adhesion, but with different kinetics and fates for the desmosomal cadherin desmoglein and for E-cadherin. Downregul...

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Bibliographic Details
Main Authors: Miquella G. Chavez, Christian A. Buhr, Whitney K. Petrie, Angela Wandinger-Ness, Donna F. Kusewitt, Laurie G. Hudson
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/309587