β-Cyclodextrin Inclusion Complex to Improve Physicochemical Properties of Pipemidic Acid: Characterization and Bioactivity Evaluation

β-Cyclodextrin Inclusion Complex to Improve Physicochemical Properties of Pipemidic Acid: Characterization and Bioactivity Evaluation

The aptitude of cyclodextrins (CDs) to form host-guest complexes has prompted an increase in the development of new drug formulations. In this study, the inclusion complexes of pipemidic acid (HPPA), a therapeutic agent for urinary tract infections, with native β-CD were prepared in solid state by k...

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Bibliographic Details
Main Authors: Gaetano Malgieri, Luigi Russo, Marina Isidori, Chiara Russo, Agostino Russo, Margherita Lavorgna, Jolanda Valentina Caso, Filomena Rapuano, Carla Isernia, Rosa Iacovino
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:International Journal of Molecular Sciences
Subjects:
β-cyclodextrin
pipemidic acid
inclusion complex
microbial activity
antitumoral activity
Online Access:http://www.mdpi.com/1422-0067/14/7/13022

Internet

http://www.mdpi.com/1422-0067/14/7/13022

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