Integrating CD4+ T cell help for therapeutic cancer vaccination in a preclinical head and neck cancer model

Integrating CD4+ T cell help for therapeutic cancer vaccination in a preclinical head and neck cancer model

Head and neck squamous cell carcinomas (HNSCC) are well suited for cancer vaccination strategies. In addition to tumor-associated antigens (TAAs) and endogenous retrovirus (ERV) encoded proteins, HNSCCs have a relatively high tumor mutational burden encoding potential neoepitopes. Peptide vaccine ca...

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Bibliographic Details
Main Authors: Hirofumi Shibata, Na Xu, Shin Saito, Liye Zhou, Ibrahim Ozgenc, Jason Webb, Cong Fu, Paul Zolkind, Ann Marie Egloff, Ravindra Uppaluri
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
head and neck cancer
cancer vaccination
mhc-ii epitope
cd4+ t cell help
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1958589

Internet

http://dx.doi.org/10.1080/2162402X.2021.1958589

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