Oncogenic ZEB2/miR-637/HMGA1 signaling axis targeting vimentin promotes the malignant phenotype of glioma

Oncogenic ZEB2/miR-637/HMGA1 signaling axis targeting vimentin promotes the malignant phenotype of glioma

Glioma is the most common primary tumor of the central nervous system. We previously confirmed that zinc finger E-box binding homeobox (ZEB) 2 promotes the malignant progression of glioma, while microRNA-637 (miR-637) is associated with favorable prognosis in glioma. This study aimed to investigate...

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Bibliographic Details
Main Authors: Yu Zeng, Tianshi Que, Jie Lin, Zhengming Zhan, Anqi Xu, Zhiyong Wu, Cheng Xie, Jie Luo, Shengfeng Ding, Hao Long, Xian Zhang, Ye Song
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
glioma
ZEB2
miR-637
HMGA1
vimentin
migration
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120304108

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http://www.sciencedirect.com/science/article/pii/S2162253120304108

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