Serial counts of <it>Mycobacterium tuberculosis</it> in sputum as surrogate markers of the sterilising activity of rifampicin and pyrazinamide in treating pulmonary tuberculosis

<p>Abstract</p> <p>Background</p> <p>Since the sterilising activity of new antituberculosis drugs is difficult to assess by conventional phase III studies, surrogate methods related to eventual relapse rates are required.</p> <p>Methods</p> <p>A...

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Bibliographic Details
Main Authors: Mitchison Denis, Odhiambo Joseph, Brindle Richard
Format: Article
Language:English
Published: BMC 2001-11-01
Series:BMC Pulmonary Medicine
Online Access:http://www.biomedcentral.com/1471-2466/1/2