Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
Elucidation of prion protein (PrP) functions is crucial to fully understand prion diseases. A major approach to studying PrP functions is the use of PrP gene-knockout (Prnp-/-) mice. So far, six types of Prnp-/- mice have been generated, demonstrating the promiscuous functions of PrP. Recently, othe...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-01-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00075/full |