Survival of the fittest: positive selection of CD4+ T cells expressing a membrane-bound fusion inhibitor following HIV-1 infection.

Survival of the fittest: positive selection of CD4+ T cells expressing a membrane-bound fusion inhibitor following HIV-1 infection.

Although a variety of genetic strategies have been developed to inhibit HIV replication, few direct comparisons of the efficacy of these inhibitors have been carried out. Moreover, most studies have not examined whether genetic inhibitors are able to induce a survival advantage that results in an ex...

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Bibliographic Details
Main Authors: Janine Kimpel, Stephen E Braun, Gang Qiu, Fay Eng Wong, Michelle Conolle, Jörn E Schmitz, Christian Brendel, Laurent M Humeau, Boro Dropulic, John J Rossi, Annemarie Berger, Dorothee von Laer, R Paul Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2925957?pdf=render

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http://europepmc.org/articles/PMC2925957?pdf=render

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