Kurarinone Attenuates Collagen-Induced Arthritis in Mice by Inhibiting Th1/Th17 Cell Responses and Oxidative Stress

Kurarinone Attenuates Collagen-Induced Arthritis in Mice by Inhibiting Th1/Th17 Cell Responses and Oxidative Stress

Kurarinone is a flavanone, extracted from <i>Sophora flavescens</i> Aiton, with multiple biological effects. Here, we determine the therapeutic potential of kurarinone and elucidate the interplay between kurarinone and the autoimmune disease rheumatoid arthritis (RA). Arthritis was recap...

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Bibliographic Details
Main Authors: Kuo-Tung Tang, Chi-Chien Lin, Shih-Chao Lin, Jou-Hsuan Wang, Sen-Wei Tsai
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
kurarinone
arthritis
Th1
Th17
STAT1
STAT3
Online Access:https://www.mdpi.com/1422-0067/22/8/4002

Internet

https://www.mdpi.com/1422-0067/22/8/4002

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