The transcription factor c-Jun protects against liver damage following activated β-Catenin signaling.

BACKGROUND: The Wnt/β-Catenin signaling pathway is central for liver functions and frequently deregulated in hepatocellular carcinoma (HCC). Analysis of the early phenotypes and molecular events following β-Catenin activation is therefore essential for better understanding HCC pathogenesis. The AP-1...

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Bibliographic Details
Main Authors: Claudia Trierweiler, Hubert E Blum, Peter Hasselblatt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3391288?pdf=render