A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients

A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients

Abstract Background With the recent emergence of immune checkpoint inhibitors, microsatellite instability (MSI) status has become an important biomarker for immune checkpoint blockade therapy. There are growing technical demands for the integration of different genomic alterations profiling includin...

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Bibliographic Details
Main Authors: Kai Zheng, Hua Wan, Jie Zhang, Guangyu Shan, Ningning Chai, Dongdong Li, Nan Fang, Lina Liu, Jingbo Zhang, Rong Du, Qixi Wu, Xichuan Li, Chunze Zhang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Translational Medicine
Subjects:
Microsatellite instability (MSI)
NGS
Colorectal cancer (CRC)
Immunotherapy
Mismatch repair
TCF7L2
Online Access:http://link.springer.com/article/10.1186/s12967-020-02373-1

Internet

http://link.springer.com/article/10.1186/s12967-020-02373-1

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