When heat casts a spell on the DNA damage checkpoints

Peregrine Laziosi (1265–1345), an Italian priest, became the patron saint of cancer patients when the tumour in his left leg miraculously disappeared after he developed a fever. Elevated body temperature can cause tumours to regress and sensitizes cancer cells to agents that break DNA. Why hyperther...

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Bibliographic Details
Main Authors: Thomas Turner, Thomas Caspari
Format: Article
Language:English
Published: The Royal Society 2014-01-01
Series:Open Biology
Subjects:
atr
atm
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.140008