Apocryphal FADS2 activity promotes fatty acid diversification in cancer

Apocryphal FADS2 activity promotes fatty acid diversification in cancer

Summary: Canonical fatty acid metabolism describes specific enzyme-substrate interactions that result in products with well-defined chain lengths, degree(s), and positions of unsaturation. Deep profiling of lipids across a range of prostate cancer cell lines reveals a variety of fatty acids with unu...

Full description

Bibliographic Details
Main Authors: Reuben S.E. Young, Andrew P. Bowman, Elizabeth D. Williams, Kaylyn D. Tousignant, Charles L. Bidgood, Venkateswara R. Narreddula, Rajesh Gupta, David L. Marshall, Berwyck L.J. Poad, Colleen C. Nelson, Shane R. Ellis, Ron M.A. Heeren, Martin C. Sadowski, Stephen J. Blanksby
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Cell Reports
Subjects:
lipids
fatty acids
unsaturation
isomer
desaturase
elongase
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721000516

Internet

http://www.sciencedirect.com/science/article/pii/S2211124721000516

Similar Items