Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion.

The deregulation of metabolism is a hallmark of aging. As such, changes in the expression of metabolic genes and the profiles of amino acid levels are features associated with aging animals. We previously reported that the levels of most amino acids decline with age in Caenorhabditis elegans (C. ele...

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Bibliographic Details
Main Authors: Yasmine J Liu, Georges E Janssens, Rebecca L McIntyre, Marte Molenaars, Rashmi Kamble, Arwen W Gao, Aldo Jongejan, Michel van Weeghel, Alyson W MacInnes, Riekelt H Houtkooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6424468?pdf=render