Effect of acadesine on breast cancer cells under hypoxia

Effect of acadesine on breast cancer cells under hypoxia

The riboside derivative acadesine (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) is currently being tested in clinical trials as a promising anti-tumor drug. Intracellular target of acadesine is adenosine monophosphate-activated protein kinase (АМРК), an important regulatory molecule of energ...

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Bibliographic Details
Main Authors: A. M. Shcherbakov, N. E. Vavilov, O. E. Andreeva, B. V. Tyaglov, A. S. Mironov, R. S. Shakulov, K. V. Lobanov, S. V. Yarotskiy, A. A. Shtil’
Format: Article
Language:Russian
Published: ABV-press 2017-04-01
Series:Uspehi Molekulârnoj Onkologii
Subjects:
acadesine
breast cancer
mcf-7 cell line
hypoxia
transcription factors
Online Access:https://umo.abvpress.ru/jour/article/view/90

Internet

https://umo.abvpress.ru/jour/article/view/90

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