Gene expression changes of single skeletal muscle fibers in response to modulation of the mitochondrial calcium uniporter (MCU)

The mitochondrial calcium uniporter (MCU) gene codifies for the inner mitochondrial membrane (IMM) channel responsible for mitochondrial Ca2+ uptake. Cytosolic Ca2+ transients are involved in sarcomere contraction through cycles of release and storage in the sarcoplasmic reticulum. In addition cytos...

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Bibliographic Details
Main Authors: Francesco Chemello, Cristina Mammucari, Gaia Gherardi, Rosario Rizzuto, Gerolamo Lanfranchi, Stefano Cagnin
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Genomics Data
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015000860