Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway

Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway

Abstract Backgrounds Glioma is the most fatal primary brain glioma in central nervous system mainly attributed to its high invasion. Prucalopride, a Serotonin-4 (5-HT4) receptor agonist, has been reported to regulate neurodevelopment. This study aimed to investigate the influence of the Prucalopride...

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Bibliographic Details
Main Authors: Hong Qiao, Yong-Bo Wang, Yu-Mei Gao, Li-Li Bi
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Neurology
Subjects:
Prucalopride
Glioma
Proliferation
Autophagy
AKT-mTOR pathway
Online Access:http://link.springer.com/article/10.1186/s12883-018-1083-7

Internet

http://link.springer.com/article/10.1186/s12883-018-1083-7

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