High Migration and Invasion Ability of PGCCs and Their Daughter Cells Associated With the Nuclear Localization of S100A10 Modified by SUMOylation

High Migration and Invasion Ability of PGCCs and Their Daughter Cells Associated With the Nuclear Localization of S100A10 Modified by SUMOylation

Our previous studies have confirmed that cobalt chloride (CoCl2) or chemoradiotherapy could induce the formation of polyploid tumor giant cells (PGCCs). Polyploid giant cancer cells are a special subpopulation of cancer cells that contribute to solid tumor heterogeneity. The size of PGCC was at leas...

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Bibliographic Details
Main Authors: Qi Zhao, Kexin Zhang, Zugui Li, Hao Zhang, Fangmei Fu, Junjie Fu, Minying Zheng, Shiwu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
S100A10
polyploidy giant cancer cells
SUMOylation
colorectal cancer
cell infiltration and migration
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.696871/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.696871/full

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