Genome-scale screening of drug-target associations relevant to Ki using a chemogenomics approach.

The identification of interactions between drugs and target proteins plays a key role in genomic drug discovery. In the present study, the quantitative binding affinities of drug-target pairs are differentiated as a measurement to define whether a drug interacts with a protein or not, and then a che...

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Bibliographic Details
Main Authors: Dong-Sheng Cao, Yi-Zeng Liang, Zhe Deng, Qian-Nan Hu, Min He, Qing-Song Xu, Guang-Hua Zhou, Liu-Xia Zhang, Zi-xin Deng, Shao Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618265?pdf=render