Positive feedback loop of FAM83A/PI3K/AKT/c-Jun induces migration, invasion and metastasis in hepatocellular carcinoma

Positive feedback loop of FAM83A/PI3K/AKT/c-Jun induces migration, invasion and metastasis in hepatocellular carcinoma

FAM83A is part of an 8-member protein family of unknown function and is reported to be a cancer-promoting and treatment-resistance factor in several cancers. However, its role in hepatocellular carcinoma (HCC) remains unclear. Analysis of the Cancer Genome Atlas (TCGA) showed that FAM83A mRNA expres...

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Bibliographic Details
Main Authors: Chen Liu, Xuemei Peng, Yonghao Li, Shu Liu, Rentao Hou, Yewei Zhang, Shi Zuo, Zhan Liu, Rongcheng Luo, Libo Li, Weiyi Fang
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
HCC
FAM83A
PI3K/AKT
EMT
Metastasis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219354022

Internet

http://www.sciencedirect.com/science/article/pii/S0753332219354022

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