Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1

Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1

Purpose: In several multicenter clinical trials, HLA-DR was found to be a potential biomarker of dry eye disease (DED)'s severity and prognosis. Given the fact that HLA-DR receptor is a heterodimer consisting in an alpha and a beta chain, we intended to investigate the correlation of inflammato...

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Bibliographic Details
Main Authors: Karima Kessal, Hong Liang, Ghislaine Rabut, Philippe Daull, Jean-Sébastien Garrigue, Mylene Docquier, Stéphane Melik Parsadaniantz, Christophe Baudouin, Françoise Brignole-Baudouin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
HLA-DR
inflammatory targets
NanoString® assay
conjunctival imprints
dry eye disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02271/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02271/full

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