Formation and Detection of Highly Oxidized Hemoglobin Forms in Biological Fluids during Hemolytic Conditions

Hemolytic diseases are characterized by an accelerated breakdown of red blood cells (RBCs) and the release of hemoglobin (Hb). Following, RBC lysis Hb oxidation occurs with the formation of different redox states of Hb (metHb and ferrylHb) and the release of heme. ferrylHb is unstable and decomposes...

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Main Authors: Benard Bogonko Nyakundi, Judit Erdei, Andrea Tóth, Enikő Balogh, Andrea Nagy, Béla Nagy, László Novák, László Bognár, György Paragh, János Kappelmayer, Viktória Jeney
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/8929020