miR‐30b protects nigrostriatal dopaminergic neurons from MPP(+)‐induced neurotoxicity via SNCA

Abstract Objective To explore the function of miR‐30b in pathogenesis of Parkinson's disease (PD) and its underlying molecular mechanism. Materials and Methods We used 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPP(+)) as a tool for constructing the PD cell model, using miR‐30b mimics or inh...

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Bibliographic Details
Main Authors: Yu‐fei Shen, Zhuo‐ying Zhu, Shu‐xia Qian, Cong‐ying Xu, Yan‐ping Wang
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.1567