Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells

Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells

Hepatocyte-like cells (HLCs) differentiated from human induced pluripotent stem cells (iPSCs) offer an alternative model to primary human hepatocytes to study lipid aberrations. However, the detailed lipid profile of HLCs is yet unknown. In the current study, functional HLCs were differentiated from...

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Bibliographic Details
Main Authors: Mostafa Kiamehr, Leena E. Viiri, Terhi Vihervaara, Kaisa M. Koistinen, Mika Hilvo, Kim Ekroos, Reijo Käkelä, Katriina Aalto-Setälä
Format: Article
Language:English
Published: The Company of Biologists 2017-09-01
Series:Disease Models & Mechanisms
Subjects:
Induced pluripotent stem cell
iPSC
Hepatocyte-like cell
HLC
Differentiation
Cell model
Lipidomics
Fatty acid
Online Access:http://dmm.biologists.org/content/10/9/1141

Internet

http://dmm.biologists.org/content/10/9/1141

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