Long-Term Effects of Ivabradine on Cardiac Vagal Parasympathetic Function in Normal Rats

Long-Term Effects of Ivabradine on Cardiac Vagal Parasympathetic Function in Normal Rats

Background: The complex interactions that exist between the pacemaker current, If, and the parasympathetic nervous system could significantly influence the course of patients undergoing chronic therapy with the If blocker ivabradine. We thus aimed to assess the effects of chronic ivabradine therapy...

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Bibliographic Details
Main Authors: Alina Scridon, Vasile Bogdan Halaţiu, Alkora Ioana Balan, Dan Alexandru Cozac, Valeriu Moldovan, Claudia Bănescu, Marcel Perian, Răzvan Constantin Şerban
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
cardioinhibitory response
HCN4
If current
ivabradine
vagal tone
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.596956/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.596956/full

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