Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine

Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine

Dehydroleucodine is a bioactive sesquiterpene lactone. Herein, four dehydroleucodine amino derivatives were synthesized using the amines proline, piperidine, morpholine, and tyramine, and spectroscopic methods and single-crystal X-ray diffraction unambiguously established their structures. The cytot...

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Bibliographic Details
Main Authors: Paola E. Ordóñez, David E. Mery, Krishan K. Sharma, Saumyadip Nemu, William F. Reynolds, Raul G. Enriquez, Darcy C. Burns, Omar Malagón, Darin E. Jones, Monica L. Guzman, Cesar M. Compadre
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
dehydroleucodine
anti-leukemic activity
sesquiterpene lactone
amino adducts
Online Access:https://www.mdpi.com/1420-3049/25/20/4825

Internet

https://www.mdpi.com/1420-3049/25/20/4825

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