GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach
Glucose-regulated protein of 78 kD (GRP78) is a chaperone protein mainly located in the endoplasmic reticulum (ER). This protein is normally present at low levels in adult cells but its expression is triggered by ER stress including glucose deprivation and hypoxia. In tumor cells, it is overexpresse...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2012-01-01
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| Series: | Journal of Oncology |
| Online Access: | http://dx.doi.org/10.1155/2012/468615 |