1H NMR-Based Metabolomics Reveals Refined-Huang-Lian-Jie-Du-Decoction (BBG) as a Potential Ischemic Stroke Treatment Drug With Efficacy and a Favorable Therapeutic Window

1H NMR-Based Metabolomics Reveals Refined-Huang-Lian-Jie-Du-Decoction (BBG) as a Potential Ischemic Stroke Treatment Drug With Efficacy and a Favorable Therapeutic Window

Huang-Lian-Jie-Du-Decoction (HLJDD) is a traditional Chinese medicine (TCM) used to treat ischemic stroke. However, the complexity of its chemical composition makes quality control difficult. Berberine, baicalin, and geniposide are the three main ingredients in HLJDD. Here, a formula of BBG comprise...

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Bibliographic Details
Main Authors: Xiaowei Fu, Junsong Wang, Shanting Liao, Yan Lv, Dingqiao Xu, Minghua Yang, Lingyi Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
Refined-Huang-Lian-Jie-Du-Decoction
berberine
baicalin
geniposide
ischemic stroke
therapeutic window
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00337/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00337/full

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