Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease

Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease

Abstract The overlapping clinical features of relapsing remitting multiple sclerosis (RRMS), aquaporin-4 (AQP4)-antibody (Ab) neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein (MOG)-Ab disease mean that detection of disease specific serum antibodies is the gold...

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Bibliographic Details
Main Authors: Maciej Jurynczyk, Fay Probert, Tianrong Yeo, George Tackley, Tim D. W. Claridge, Ana Cavey, Mark R. Woodhall, Siddharth Arora, Torsten Winkler, Eric Schiffer, Angela Vincent, Gabriele DeLuca, Nicola R. Sibson, M. Isabel Leite, Patrick Waters, Daniel C. Anthony, Jacqueline Palace
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Acta Neuropathologica Communications
Subjects:
Multiple sclerosis
Neuromyelitis optica
Metabolomics
Biomarker
MOG antibody disease
Online Access:http://link.springer.com/article/10.1186/s40478-017-0495-8

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http://link.springer.com/article/10.1186/s40478-017-0495-8

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