Tax-1 and Tax-2 similarities and differences: Focus on post-translational modifications and NF-кB activation

Tax-1 and Tax-2 similarities and differences: Focus on post-translational modifications and NF-кB activation

ABSTRACTAlthough human T-cell leukemia virus type 1 and 2 (HTLV-1 and HTLV-2) share similar genetic organization, they have major differences in their pathogenesis and disease manifestation. HTLV-1 is capable of transforming T lymphocytes in infected patients and subsequently leads to adult T cell l...

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Bibliographic Details
Main Authors: Margret eShirinian, Youmna eKfoury, Zeina eDassouki, Hiba eEl Hajj, Ali eBazarbachi
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Microbiology
Subjects:
HTLV-1
NFkB
HTLV-2
Tax-1
Tax-2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00231/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00231/full

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