Perspectives on Systems Modeling of Human Peripheral Blood Mononuclear Cells

Human peripheral blood mononuclear cells (PBMCs) are the key drivers of the immune responses. These cells undergo activation, proliferation and differentiation into various subsets. During these processes they initiate metabolic reprogramming, which is coordinated by specific gene and protein activi...

Full description

Bibliographic Details
Main Authors: Partho Sen, Esko Kemppainen, Matej Orešič
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00096/full