Cathepsin K associates with lymph node metastasis and poor prognosis in oral squamous cell carcinoma

Cathepsin K associates with lymph node metastasis and poor prognosis in oral squamous cell carcinoma

Abstract Background Lymph node metastasis (LNM) is a major determinant of prognosis and treatment planning of oral squamous cell carcinoma (OSCC). Cysteine cathepsins constitute a family of proteolytic enzymes with known role in the degradation of the extracellular matrix. Involvement in pathologica...

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Bibliographic Details
Main Authors: Frank K. Leusink, Eleftherios Koudounarakis, Michael H. Frank, Ronald Koole, Paul J. van Diest, Stefan M. Willems
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
Oral squamous cell carcinoma
Cathepsin K
Lymph node metastasis
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12885-018-4315-8

Internet

http://link.springer.com/article/10.1186/s12885-018-4315-8

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