Crystal structure of an integron gene cassette-associated protein from Vibrio cholerae identifies a cationic drug-binding module.

<h4>Background</h4>The direct isolation of integron gene cassettes from cultivated and environmental microbial sources allows an assessment of the impact of the integron/gene cassette system on the emergence of new phenotypes, such as drug resistance or virulence. A structural approach i...

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Main Authors: Chandrika N Deshpande, Stephen J Harrop, Yan Boucher, Karl A Hassan, Rosa Di Leo, Xiaohui Xu, Hong Cui, Alexei Savchenko, Changsoo Chang, Maurizio Labbate, Ian T Paulsen, H W Stokes, Paul M G Curmi, Bridget C Mabbutt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21390267/?tool=EBI