Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity

<p>Abstract</p> <p>Background</p> <p>Terpenoid derivatives originating from many plants species, are interesting compounds with numerous biological effects, such as anti-HIV-1 activity. The zinc tetra-ascorbo-camphorate complex (or "C14"), a new monoterpenoid...

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Bibliographic Details
Main Authors: Mannarini Aurèle, Charpentier Charlotte, Gombert Bernard, Jenabian Mohammad-Ali, Saïdi Héla, Bélec Laurent
Format: Article
Language:English
Published: BMC 2008-06-01
Series:AIDS Research and Therapy
Online Access:http://www.aidsrestherapy.com/content/5/1/10