The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models
TGFβ1 is a member of a large growth factor family including activins/inhibins and bone morphogenic proteins (BMPs) that have a potent growth regulatory and immunomodulatory functions in normal skin homeostasis, regulation of epidermal stem cells, extracellular matrix production, angiogenesis, and in...
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Journal of Skin Cancer |
Online Access: | http://dx.doi.org/10.1155/2012/249063 |