The role of insulin-like growth factor-I in the physiopathology of hearing

The role of insulin-like growth factor-I in the physiopathology of hearing

Insulin like growth factor I (IGF-I) belongs to the family of polypeptides of insulin, which play a central role in embryonic development and adult nervous system homeostasis by endocrine, autocrine and paracrine mechanisms. IGF-I is fundamental for the regulation of cochlear development, growth an...

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Bibliographic Details
Main Authors: Silvia eMurillo-Cuesta, Lourdes eRodríguez-de La Rosa, Luis eLassaleta, Rafael eCediel, Isabel eVarela-Nieto
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Deafness
Organ of Corti
Human genetics
Animal Models
IGF1R signaling
Insulin-like factors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00011/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00011/full

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