Optimizing a Multi-Component Intranasal Entamoeba Histolytica Vaccine Formulation Using a Design of Experiments Strategy

Optimizing a Multi-Component Intranasal Entamoeba Histolytica Vaccine Formulation Using a Design of Experiments Strategy

Amebiasis is a neglected tropical disease caused by Entamoeba histolytica. Although the disease burden varies geographically, amebiasis is estimated to account for some 55,000 deaths and millions of infections globally per year. Children and travelers are among the groups with the greatest risk of i...

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Bibliographic Details
Main Authors: Mayuresh M. Abhyankar, Mark T. Orr, Robert Kinsey, Sandra Sivananthan, Andrew J. Nafziger, David N. Oakland, Mary K. Young, Laura Farr, Md Jashim Uddin, Jhansi L. Leslie, Stacey L. Burgess, Hong Liang, Ines De Lima, Elise Larson, Jeffrey A. Guderian, Susan Lin, Aaron Kahn, Prakash Ghosh, Sierra Reed, Mark A. Tomai, Karl Pedersen, William A. Petri, Christopher B. Fox
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Entamoeba histolytica
vaccine adjuvant
TLR ligand
intranasal
liposome
formulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.683157/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.683157/full

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