Diannexin protects against renal ischemia reperfusion injury and targets phosphatidylserines in ischemic tissue.

Diannexin protects against renal ischemia reperfusion injury and targets phosphatidylserines in ischemic tissue.

Renal ischemia/reperfusion injury (IRI) frequently complicates shock, renal transplantation and cardiac and aortic surgery, and has prognostic significance. The translocation of phosphatidylserines to cell surfaces is an important pro-inflammatory signal for cell-stress after IRI. We hypothesized th...

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Bibliographic Details
Main Authors: Kimberley E Wever, Frank A D T G Wagener, Cathelijne Frielink, Otto C Boerman, Gert J Scheffer, Anthony Allison, Rosalinde Masereeuw, Gerard A Rongen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3168880?pdf=render

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http://europepmc.org/articles/PMC3168880?pdf=render

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