Enhancing the immune stimulatory effects of cetuximab therapy through TLR3 signalling in Epstein-Barr virus (EBV) positive nasopharyngeal carcinoma

Enhancing the immune stimulatory effects of cetuximab therapy through TLR3 signalling in Epstein-Barr virus (EBV) positive nasopharyngeal carcinoma

Cetuximab immunotherapy targeting the epidermal growth factor receptor (EGFR) has been used to treat nasopharyngeal cancer (NPC) with some success. Therefore, combining an immune adjuvant to boost the immune microenvironment may improve its clinical efficacy. Herein, we investigate the immune-stimul...

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Bibliographic Details
Main Authors: Louise Soo Yee Tan, Benjamin Wong, Nagaraja Rao Gangodu, Andrea Zhe Ern Lee, Anthony Kian Fong Liou, Kwok Seng Loh, Hao Li, Ming Yann Lim, Andres M. Salazar, Chwee Ming Lim
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:OncoImmunology
Subjects:
cetuximab
nasopharyngeal carcinoma (npc)
poly-l-lysine double stranded rna (poly-iclc)
polymorphisms
toll-like receptor 3 (tlr3)
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1500109

Internet

http://dx.doi.org/10.1080/2162402X.2018.1500109

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