A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth.

BACKGROUND:The stromal microenvironment and particularly the macrophage component of primary tumors influence their malignant potential. However, at the metastatic site the role of these cells and their mechanism of actions for establishment and growth of metastases remain largely unknown. METHODOLO...

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Bibliographic Details
Main Authors: Binzhi Qian, Yan Deng, Jae Hong Im, Ruth J Muschel, Yiyu Zou, Jiufeng Li, Richard A Lang, Jeffrey W Pollard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2721818?pdf=render