Endothelial GPR124 Exaggerates the Pathogenesis of Atherosclerosis by Activating Inflammation

Endothelial GPR124 Exaggerates the Pathogenesis of Atherosclerosis by Activating Inflammation

Background/Aims: Endothelial cell dysfunction is the principal pathological process underlying atherosclerotic cardiovascular disease. G protein-coupled receptor 124 (GPR124), an orphan receptor in the adhesion GPCR subfamily, promotes angiogenesis in the brain. In the present study, we explored the...

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Bibliographic Details
Main Authors: Dong-Mei Gong, Yan-Li Zhang, Dan-Yang Chen, Ling-Juan Hong, Feng Han, Qi-Bing Liu, Jian-Jun Jiang, Ying-Mei Lu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
GPR124
Endothelial
Atherosclerosis
Nitrosative stress
Inflammasome
Online Access:https://www.karger.com/Article/FullText/487032

Internet

https://www.karger.com/Article/FullText/487032

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