SOCS3 and SOCS5 mRNA expressions may predict initial steroid response in nephrotic syndrome children

SOCS3 and SOCS5 mRNA expressions may predict initial steroid response in nephrotic syndrome children

Suppressors of Cytokine Signaling (SOCS) inhibit Signal Transducers and Activators of Transcription (STATs) phosphorylation by binding and inhibiting Janus Kinases (JaKs). The aim of the present study was to evaluate the influence of glucocorticosteroids on the JaK/STAT signaling pathway in the leuk...

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Bibliographic Details
Main Authors: Witold Szaflarski, Piotr Zawierucha, Katarzyna Zaorska, Malgorzata Jaroniec, Magdalena Smiech, Danuta Ostalska-Nowicka, Agnieszka Malinska, Michal Nowicki
Format: Article
Language:English
Published: Via Medica 2012-01-01
Series:Folia Histochemica et Cytobiologica
Subjects:
JaK/STAT signaling pathway
leukocytes
nephrotic syndrome
resistance to steroids
children
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/14734

Internet

http://czasopisma.viamedica.pl/fhc/article/view/14734

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