IP Receptor Agonist–Induced DNA Synthesis and Proliferation in Primary Cultures of Adult Rat Hepatocytes: the Involvement of Endogenous Transforming Growth Factor-α
To elucidate the mechanism of action of prostaglandin I2 (PGI2) and carbaprostacyclin, we studied their effect on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes. Hepatocyte parenchymal cells, maintained in a serum-free, defined medium, synthesized DNA and proliferated i...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2009-01-01
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| Series: | Journal of Pharmacological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319312459 |