Adipose-derived mesenchymal stem cells modulate CD14++CD16+ expression on monocytes from sepsis patients in vitro via prostaglandin E2

Adipose-derived mesenchymal stem cells modulate CD14++CD16+ expression on monocytes from sepsis patients in vitro via prostaglandin E2

Abstract Background Mesenchymal stem cells (MSCs) have been shown to reduce sepsis-induced inflammation and improve survival in mouse models of sepsis. CD16+ monocytes are proinflammatory and abundant in inflammatory conditions such as sepsis. The primary objective in this exploratory study was to d...

Full description

Bibliographic Details
Main Authors: Guanguan Qiu, Guoping Zheng, Menghua Ge, Lanfang Huang, Haijiang Tong, Ping Chen, Dengming Lai, Yaoqin Hu, Baoli Cheng, Qiang Shu, Jianguo Xu
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Stem Cell Research & Therapy
Subjects:
Adipose-derived mesenchymal stem (stromal) cells
CD14++CD16+
Monocytes
COX-2
PGE2
Sepsis
Online Access:http://link.springer.com/article/10.1186/s13287-017-0546-x

Internet

http://link.springer.com/article/10.1186/s13287-017-0546-x

Similar Items