Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies.

BACKGROUND:Multiplex assays are increasingly applied to analyze multicomponent signatures of human immune responses, including the dynamics of cytokine and chemokine production, in observational as well as interventional studies following treatment or vaccination. However, relatively limited informa...

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Main Authors: Krista E van Meijgaarden, Bhagwati Khatri, Steven G Smith, Anne M F H Drittij, Roelof A de Paus, Jelle J Goeman, Mei M Ho, Hazel M Dockrell, Helen McShane, Simone A Joosten, Tom H M Ottenhoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6122788?pdf=render