Improved Synthesis and Determination of the Biologically Active Diastereomer of YK11
The palladium catalyzed carbonylation of <b>1</b> using the chiral ligand <b>L1</b> afforded <b>2</b> in a highly diastereoselective manner. The stereochemistry of the major diastereomer<b> 2a</b> was determined by X-ray crystallographic analysis. AR l...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-04-01
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| Series: | Molbank |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-8599/2020/2/M1125 |