Synthesis, Molecular Docking and β-Glucuronidase Inhibitory Potential of Indole Base Oxadiazole Derivatives

Synthesis, Molecular Docking and β-Glucuronidase Inhibitory Potential of Indole Base Oxadiazole Derivatives

β-glucuronidase is a lysosomal glycosidase enzyme which catalyzes the extracellular matrix of cancer and normal cells and the glycosaminoglycans of the cell membrane, which is important for cancer cell proliferation, invasion, and metastasis. Liver cancer, colon carcinoma, and neoplasm blad...

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Bibliographic Details
Main Authors: El Hassane Anouar, Moustapha Eid Moustapha, Muhammad Taha, Mohammed H. Geesi, Zeinab R. Farag, Fazal Rahim, Noor Barak Almandil, Rai Khalid Farooq, Muhammad Nawaz, Ashik Mosaddik
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
synthesis
indole
oxadiazole
β-glucuronidase
molecular docking
SAR
Online Access:http://www.mdpi.com/1420-3049/24/5/963

Internet

http://www.mdpi.com/1420-3049/24/5/963

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