Delayed cutaneous wound healing and aberrant expression of hair follicle stem cell markers in mice selectively lacking Ctip2 in epidermis.

COUP-TF interacting protein 2 [(Ctip2), also known as Bcl11b] is an important regulator of skin homeostasis, and is overexpressed in head and neck cancer. Ctip2(ep-/-) mice, selectively ablated for Ctip2 in epidermal keratinocytes, exhibited impaired terminal differentiation and delayed epidermal pe...

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Bibliographic Details
Main Authors: Xiaobo Liang, Shreya Bhattacharya, Gaurav Bajaj, Gunjan Guha, Zhixing Wang, Hyo-Sang Jang, Mark Leid, Arup Kumar Indra, Gitali Ganguli-Indra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283611?pdf=render