Are There Common Mechanisms Between the Hutchinson–Gilford Progeria Syndrome and Natural Aging?

Are There Common Mechanisms Between the Hutchinson–Gilford Progeria Syndrome and Natural Aging?

The Hutchinson–Gilford progeria syndrome (HGPS) is a premature aging disease caused by mutations of the LMNA gene leading to increased production of a partially processed form of the nuclear fibrillar protein lamin A – progerin. Progerin acts as a dominant factor that leads to multiple morphological...

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Bibliographic Details
Main Authors: Vasily V. Ashapkin, Lyudmila I. Kutueva, Svetlana Y. Kurchashova, Igor I. Kireev
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
aging
epigenetics
lamin
progerin
rejuvenation
reprogramming
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00455/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00455/full

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