Coxsackievirus B3 directly induced Th17 cell differentiation by inhibiting Nup98 expression in patients with acute viral myocarditis

Th17 cells play a key role in the progression of coxsackievirus B3 (CVB3)-induced acute viral myocarditis (AVMC). However, the direct effect of virus on Th17 cell differentiation is still unknown. Recently, nucleoporin (Nup) 98 has been proved to be associated with lymphocyte differentiation. Theref...

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Bibliographic Details
Main Authors: Qi Long, Yu-Hua Liao, Yu Xie, Wei Liang, Xiang Cheng, Jing Yuan, Miao Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00171/full